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This is the brand’s first prescription acne treatment and primer.
October 21, 2025
By: Rachel Klemovitch
Assistant Editor
Curology, a dermatologist-developed and personalized skincare brand, launched DayPrimeRx, the first-ever prescription acne treatment and blurring primer in one.
Designed for daytime use, DayPrimeRx is an innovative breakthrough in acne care, combining clinical efficacy with beauty benefits to meet the everyday needs of people living with acne.
Dr. Whitney Tolpinrud, MD, FAAD, Board-Certified Dermatologist and Medical Director at Curology, said,
“DayPrimeRx solves one of the most vexing challenges in beauty and skincare – the fact that acne treatments don’t often layer well under makeup, forcing people to choose between cover and treat. DayPrimeRx eliminates that choice, giving patients one product that immediately blurs the skin, treats skin with prescription actives over time, and holds makeup in place for up to 12 hours thereby maximizing results and minimizing effort.”
DayPrimeRx is a hybrid formula with two key differentiators: personalization and primer.
Developed by Curology’s expert dermatologists alongside cosmetic chemists, DayPrimeRx’s revolutionary formula provides an instant blurring effect and smoother-looking skin with or without makeup.
Curology’s prescription treatment blends three active ingredients to target an individual’s unique skin goals, such as acne, dark spots, rosacea, and more, while the primer base visibly blurs imperfections, minimizes the look of pores, evens out skin texture, and holds makeup in place for up to 12 hours.
To get the prescription, new patients start with a consultation where they share their medical history, along with current skin concerns, goals, and a few photos for our medical team to review.
An in-house licensed dermatology provider will evaluate the photos and information, then craft a personalized treatment plan. As part of that plan, Curology providers prescribe a personalized formula with up to 3 clinically proven active ingredients based on a variety of factors specific to the patient.
Curology dermatologists recommend a streamlined daily routine in addition to personalized prescription formulas, consisting of cleansers, serums, moisturizers, and sunscreen.
These can be added, and these products, along with your prescription, are sent right to your door every two months.
Curology Expands into Walmart Stores Nationwide
BoldHue Personalized Foundation Device Gains $3.3 Million in Funding
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